Heterogeneity of Depression in MCI: Relations with Cognition

 


   Note: An Official Proposal has not been Submitted to NACC.


   Lead Investigator:    Ross Divers
   Institution      :    Louisiana State University
   E-Mail           :    rdiver1@lsu.edu
   Proposal ID      :    1764



   Proposal Description:
   Depression is common in older adults with MCI, and is associated with cognitive  and functional decline. It is less well known if specific kinds or combinations  of depression symptoms differ in how they contribute to cognitive dysfunction  in this population. The first aim of the current study is to examine  heterogeneity of depression symptoms of those with MCI using factor mixture  modeling. The second aim of the current study is to examine if there are  differences in cognition across depression symptom classes created in the first  aim.